Esco TL Time Lapse IVF incubator Instruction Manual

TL Time Lapse IVF incubator

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Specifications

• Overall Dimensions (W x D x H): 805 x 590 x 375 mm (31.7 x 23.2
  x 14.8 inches)

• Chamber Dimensions: 950 x 685 x 375 mm (37.4 x 27.0 x 14.8
  inches)

• Temperature Control Range

• Gas Consumption (CO2): < 2 L/h

• Gas Consumption (N2): < 5 L/h

• CO2 Control Range: 2.9% – 9.9%

• O2 Control Range: 2.0% – 20.0%

• Input Gas Pressure: 5.0% – 20.0%

• Built-in Microscope: Zeiss 20x, objective with numerical
  aperture of 0.35, specialized for 635 nm illumination

• Embryo Illumination: 0.064s per image, using 1W single red LED
  (635nm)

• Camera Resolution: 1280 x 1024 Monochrome, 8-bit, IDS
  system

• Optics Tube Ratio: 5, 10, and 20 min intervals in 3, 5, and 7
  focal planes

Product Usage Instructions

Setting Up the Incubator

1. Place the incubator on a stable, level surface with proper
   ventilation.

2. Connect the necessary gas supply lines according to the input
   gas pressure requirements.

3. Ensure the microscope and camera components are properly
   aligned and functional.

Operating the Incubator

1. Power on the incubator and allow it to reach the desired
   temperature and gas concentrations.

2. Load the embryos into the chamber carefully to avoid any
   damage.

3. Close the lid securely to maintain the optimal environment
   inside the chamber.

Maintaining the Incubator

1. Regularly clean and sterilize the interior surfaces of the
   chamber to prevent contamination.

2. Check and calibrate the temperature and gas controls
   periodically to ensure accurate settings.

FAQ

Q: What is the lifetime of the incubator?

A: The incubator has a lifetime of 2 years and undergoes gamma
irradiation for sterilization.

Q: How do I conduct quality checking using the annotation

tools?

A: You can easily navigate through the stacked timeline, play
individual videos, annotate, and compare each embryo for quality
checking purposes.

Q: What are the biocompatibility tests conducted on the

product?

A: The product undergoes Mouse Embryo Assay (MEA) test with
thawed embryos and Limulus Amebocyte Lysate (LAL) test to ensure
biocompatibility.

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MIRI® Incubators
for Embryo Culture Incubation

table of contents
About Esco Medical ……………………………………………………………………………….03 About Embryo Culture ………………………………………………………………………..04 MIRI® Time-Lapse Incubator ……………………………………………………………………06 CultureCoin® ……………………………………………………………………………………….06 Multiroom Incubator ……………………………………………………………………………08
MIRI® ………………………………………………………………………………………….08 MIRI® II-12 ………………………………………………………………………………………09 Mini MIRI® Dry and Humidity Incubators ………………………………………………..11 Heating Optimization Plates for MIRI® multiroom IVF incubators………….12 Quality Assurance and Validation Units………………………………..13 MIRI® GA…………………………………………………………………………………….13
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About Esco
Welcome to Esco
Since the establishment of Esco in 1978, we never stopped developing, providing, and delivering innovative solutions. From one, we have progressed into four business units with a worldwide presence, namely Esco Scientific, Esco Healthcare, Esco Medical, and Esco Aster–remaining true to our tagline “World-class. Worldwide.” Last 2020, we shifted from Esco Group of Companies to Esco Lifesciences Group, carrying a new tagline “Improving lives through science”. The transformation of the company name and brand signifies Esco’s vigor in keeping up, responsive, and adaptive with the fastchanging world while keeping focused on its mission to deliver enabling technologies and provide service all over the world – and improve lives through science.
At Esco Medical, life has begun
Esco Medical is one of the divisions of the Esco Lifesciences Group, apart from Esco Scientific, Esco Healthcare and Esco Aster. Esco Medical provides innovative technological solutions for fertility clinics and laboratories. The slightest deviation, usually considered as insignificant, often result in non- optimal conditions for embryo growth and lowered pregnancy success. In Esco, we understand that even the smallest details affect the In Vitro Fertilization process. Thus, Esco Medical’s primary focus is to provide fertility technologies and solutions to help the world’s leading IVF centers to improve, standardize and automate their processes in order to achieve better clinical outcomes and patient satisfaction. Esco Medical is the leading manufacturer and innovator of high-quality equipment such as Time-Lapse Incubator, Multiroom Embryo Incubators, IVF Workstation, CO2 Incubator, Anti-Vibration Table, and Gas Analyser. Most of our medical products are designed in Denmark and made in the EU.
I promise… I’ll raise you like flying a kite. Will hold you with both hands and slowly let go. The day you fly, I’ll watch you chase the sky.
3

About Embryo Culture
Embryo incubation is a crucial step in all In Vitro Fertilization (IVF) procedures. The process involves the development of embryos in culture dishes using a suitable media, in a specific incubator, through different stages such as fertilization, cleavage, and blastocyst. IVF is an Assisted Reproductive Technology that requires incubators to provide a temporary environment for embryos before they are implanted back into the female. IVF incubators are designed to mimic the woman’s uterine environment, which is essential for embryo development. Therefore, IVF laboratories consider culture incubators as critical equipment as they provide a stable and suitable environment, reducing environmental stress to gametes. The incubators control parameters such as carbon dioxide levels/pH, oxygen concentration, humidity/evaporation/media osmolality, and temperature, which affect embryo development. Esco Medical offers a range of incubator models suitable for the needs of IVF laboratories and clinics. This catalogue will guide and inform you about Esco Medical’s different incubators.
4

5

MIRI® Time-Lapse Incubator

MIRI® TL is a Time-Lapse incubator that monitors embryo development. The MIRI® TL, optimized for clinical and IVF procedures, is designed to support existing work and quality assurance routines. This value-added treatment provides the most unique incubation environment with the market’s most secure and safest procedures. It lessens disturbance and minimizes stressful factors that may be introduced when taking the dishes out of the incubator. This incubation system also ensures predictability in the daily handling and currently offers the market’s lowest cost of ownership.

Unique Incubation Environment
· Has independent multi-chamber system. · Gas recirculation through VOC/HEPA filters and UV light. · Built-in gas mixer. Premixed gas is not required.

MIRI® TL6: 6 Individual chambers. MIRI® TL12: 12 Individual chambers.

Gas recovery: less than three (3) minutes. Temperature recovery: less than one (1) minute.

Unprecedented Faster Recovery

*When the lid has not been opened for more than 30 sec.

· Excellent recovery time for both temperature and gas parameters. · Opening one chamber will have no impact on the rest of the system. · Heated upper lid and bottom plate for excellent temperature regulation and uniformity.

2 Temperature Mode Options: · Single: Uniform setpoints for all 6 (six) or 12 (twelve) chambers. · Multi: Individual setpoints for each chamber.

Sophisticated Annotation Tools
· Freedom to personalize instrument and parameter settings. · Do a side-by- side comparison and compare actual timings to ideal.
Quality checking an easy breeze!
· Has 12 or 24 temperature sensors to ensure constant temperature stability. · Independent PT1000 sensors and gas sample ports for external validation. · Built-in pH measuring system. · Data logging system.

This equipment is a CE-marked device and is in conformity with the essential requirements of the medical devices EU regulation 2017/745.

Embryo Analysis and Evaluation System
The MIRI® TL Viewer Software is a simple yet sophisticated information- providing tool that can help embryologists process the data generated. You can review, annotate and compare the morphokinetic parameters of each embryo to select or deselect embryos for transfer and export data for retrospective analysis.

Navigation through the stacked timeline is easy and intuitive as the
revolver shows the videos of the 14 wells of one single CultureCoin®. You
can play the individual videos, annotate and compare each single embryo. Shown on the image is a magnified view of embryo #8

Measurement tool The user can now conduct precise measurement procedures
to ensure the most optimal embryo development.

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General Specifications MIRI® TL Multiroom IVF Incubators

Specifications
Overall Dimensions (W x D x H) Chamber Dimensions
Temperature Control Range *Gas Consumption (CO2) **Gas Consumption (N2) CO2 Control Range O2 Control Range Input Gas Pressure
Built-in Microscope
Embryo Illumination
Camera Resolution
Optics Tube Ratio
Imaging Focal Planes

TL6

TL12

805 x 590 x 375 mm (31.7 x 23.2 x 14.8″ )

950 x 685 x 375 mm (37.4 x 27.0 x 14.8″)

120 x 90 x 26 mm (4.7 x 3.5 x 1″)

28.7 – 41.0 °C

< 2 L/h

< 5 L/h

2.9% – 9.9%

2.0% – 20.0%

5.0% – 20.0%

0.4 ­ 0.6 bar (5.80 ­ 8.70 PSI)

Zeiss 20x, objective has numerical aperture of 0.35, specialized for 635 nm illumination

0.064s per image, using 1W single red LED (635nm)

1280 x 1024. Monochrome, 8-bit, IDS system

2.22 px/µm

5, 10 and 20 min intervals in 3, 5 and 7 focal planes

• Under normal condition (CO2 setpoint reached at 6.0%, all lids closed). ** Under normal condition (O2 setpoint reached at 5.0%, all lids closed).

Ordering Information

ITEM CODE Unit
2070091 2070092 2070100 2070101 MIRI® TL Viewer Software
2070042 1320095 Accessories 1320011 1320088 1320045

MODEL CODE
MRI-TL-MN-6C-8 MRI-TL-MN-6C-9
MRI-TL-12C-8 MRI-TL-12C-9
MRI-VIEWER MRI-SERVER
MRA-1007 MRI-CC MRI-GA

DESCRIPTION
MIRI® Time-Lapse Incubator, Mini, 6 Chambers, 230 V, 50/60 Hz MIRI® Time-Lapse Incubator, Mini, 6 Chambers, 115 V, 50/60 Hz
MIRI® Time-Lapse Incubator, 12 Chambers, 230 V, 50/60 Hz MIRI® Time-Lapse Incubator, 12 Chambers, 115 V, 50/60 Hz
MIRI® Time-Lapse Viewer MIRI® Time-Lapse Server
HEPA + VOC filter (to be replaced every 3 months) CultureCoin® for Time-Lapse of 14 embryos (25 pcs. per pack) MIRI® GA CO2/O2 & Temperature Validation Unit, 115V/ 230V

CultureCoin® for MIRI® TL
· Holds up to 14 embryos with individual numbered wells (1-14). · For single and separated culture where each embryo are cultured in its own environment. · Ergonomic design for easy handling and location of embryos. · Separate well for pH measurements. · Oxygen plasma treated for high wet-ability (hydroscopic). · Packed in 1 dish pouches and delivered in boxes of 25 pcs.

General Specifications

Overall dimensions (Diameter x Height)

Ø 71 x 10 mm

Empty weight Material
Incubation Temperature range Incubation CO2 range Incubation O2 range Sterilization method Lifetime

Styrene Methyl Methacrylate (SMMA) 28.7 ­ 40.0 oC 1.9 ­ 10% 4.9 ­ 20.0%
Gamma Irradiation 2 year

Biocompatibility Tests

1. Mouse Embryo Assay (MEA) test with thawed 1-cell mouse embryos. Acceptance criteria: at least 80% of embryos developed to the blastocyst stage. 2. Limulus Amebocyte Lysate (LAL) test. Acceptance criteria: < 20 EU/device

Ordering Information

ITEM CODE

MODEL CODE

DESCRIPTION

1320088

MRI-CC

CultureCoin® for Time-Lapse of 14 embryos

7

Multiroom Incubator

MIRI® Incubation System

The Top-of-the-Line Features of the MIRI® Incubation System

· Heated Lid Prevents condensation. Enhances temperature regulation.

· Direct Heat Transfer Provides superior temperature stability.

· Completely Independent Chambers Any disruption (e.g., temperature drop after opening the lid) has zero impact on the rest of the system.

· A Complete Incubation Environment Has a built-in gas mixer. Premixed gas is not required. Built-in pH measuring system and data logging system.

MIRI® Multiroom Incubator
The MIRI® is a revolution, in form and functionality, of CO2 incubators for In Vitro Fertilization (IVF). With 6 chambers, the MIRI® is a Multiroom Incubator that allows users to access their cultures in one chamber without affecting the neighbouring chambers. Thus, the harmful effects of fluctuations in temperature and gas caused by frequent incubator access are avoided. Built specifically to equip IVF laboratories and clinics to provide the best standard of care, it boasts a unique set of features that cannot be found elsewhere.
Key Features
Fast Recovery · <1 minute temperature recovery. · <3 minutes gas recovery.
*If the lid has not been opened for more than 30 sec.
Built-in pH meter For accurate validation.
Solid Validation System · Six (6) PT1000 sensors and Gas ports for
validation outputs · External Data Logging. · Alarm relay contact.

Supreme Capacity
· Total capacity of up to 48 standard culture dishes.
Excellent Gas System
· Separate CO2 and O2 regulation, expensive mixed gases not required!
· Air is continuously cleaned by VOC/HEPA filters, and UV light. (not applicable to MIRI® Humidity)
Stacking Frames

This equipment is a CE-marked device and is in conformity with the essential requirements of the medical devices EU
regulation 2017/745.

MRA-DRAW – MIRI® Stacking Frame for 2 units with a drawer
8

MRA-1014 – Stacking Frame for 2 units

MIRI® II-12 Multiroom Incubator

The MIRI® II-12 is an incubator that provides unique features for every IVF laboratories and clinics. The chambers are specially designed to accommodate one patient ensuring personal space for each embryo. Having an excellent footprint, MIRI® II-12 is made to perfectly fit every IVF lab.

Independent Chambers
Each chamber is specially designed for one patient. Hence, there is no disturbance to other chambers even when a lid is opened/closed.
Excellent footprint
With its compact size, it can perfectly fit in every IVF Lab.
Low gas consumption
The built-in gas mixer and efficient recirculation system allows you to save on gas consumption.

This equipment is a CE-marked device and is in conformity with the essential requirements of the medical devices EU
regulation 2017/745.

Just a fitting solution…
MIRI® II-12 comes with specific heating optimization plates matching the type of dishes used in the laboratories.
Each chamber contains a heating optimization plate to facilitate heat transfer directly to the culture dishes.
· There is a choice between various heating optimization plates.

Airflow Diagram

O2 from Atmosphere

Gas Mixing

VOC / HEPA Filtration

CO2

N2

Recirculation

UV Sterilization Table

Incubation Chambers

Total control of the gas phase environment is provided. The built-in gas mixer and the high-performance CO2 and O2 sensors allow accurate control of gas composition in the chambers.

9

General Specifications

MIRI® Multiroom IVF Incubator

Model

MIRI® Dry

MIRI® Humidity

Overall Dimensions (W x D x H) Chamber Dimensions Power Supply
Power Consumption
Temperature Control Range

• CO2 Gas Consumption **N2 Gas Consumption
  CO2 Control Range O2 Control Range
  Input Gas Pressure (CO2) Input Gas Pressure (N2) Net Weight
  Shipping Weight
  Shipping Dimension

700 x 585 x 165 mm ( 27.6 x 23.0 x 6.5″) 700 x 645 x 280 mm ( 27.6 x 25.4 x 11.0″)

200 x 176 x 25 mm (7.9 x 6.9 x 1″)

115 / 230V, 50/60 Hz

300 W

24.9 – 40°C

<2 L/h

<4 L/h

<12 L/h

2.0 – 9.9%

5.0 – 20%

0.4 – 0.6 bar (8.70 PSI)

0.4 – 0.6 bar (8.70 PSI)

40 kg (88.2 lbs)

45 kg (99.2 lbs) (Including the pallet’s weight)

824 x 724 x 489 mm (32.4 x 28.5 x 19.3″) (device on the pallet)

MIRI® II-12 Multiroom IVF Incubator

Under Under

normal normal

condition condition

((OC2O2sesteptopionitnrteraecahcehdedata5t.50.%0%, a,llallildlisdcsloclsoesde)d)

Overall Dimensions (W x D x H) Chamber Dimensions Power Supply
Power Consumption
Temperature Control Range
*CO2 Gas Consumption **N2 Gas Consumption
CO2 Control Range O2 Control Range
CO2 Input Gas Pressure N2 Input Gas Pressure Net Weight
Shipping weight
Shipping dimension

740 x 575 x 215 mm (29.1 x 22.6 x 8.5″) 120 x 90 x 26 mm (4.7 x 3.5 x 1″) 115V 50/60 Hz or 230V 50/60 Hz 500 W 25 – 40° C <2 L/h <12 L/h 3.0 – 10% 5.0 – 10% 0.4 ­ 0.6 bar (5.80 ­ 8.70 PSI) 0.4 ­ 0.6 bar (5.80 ­ 8.70 PSI) 47 kg
57 kg (121.3 lbs) (Including the pallet’s weight) 890 x 710 x 480 mm (35 x 28 x 18.9″) (device on the pallet)

• Under normal condition (CO2 setpoint reached at 5.0%, all lids closed) ** Under normal condition (O2 setpoint reached at 5.0%, all lids closed)
  Ordering Information

ITEM CODE

MODEL CODE

MIRI® Multiroom Incubator

2070047

MRI-6A10-8

2070048 1320045

MRI-6A10-9 MRI-GA

MIRI® II-12 Multiroom Incubator

2070164

MRI2-12C-8

2070165

MRI2-12C-9

DESCRIPTION
MIRI® Incubator, 230V, 50/60Hz MIRI® Incubator, 115V, 50/60Hz MIRI® GA CO2 / O2 & Temperature Validation Unit, 115V / 230V
MIRI® II-12 Incubator with 12 chambers, 230V, 50/60Hz MIRI® II-12 Incubator with 12 chambers, 115V, 50/60Hz

10

Mini MIRI® Incubator
Built on the strong and reliable MIRI® Multiroom, the Mini MIRI® is an incubator that provides a stable culture environment. It has two chambers that prevent cross-contamination while VOC/HEPA filtration cleans the incoming airstream. The compact design and direct heat regulation further translate to faster temperature and gas recovery.
Comes in two models:
Mini MIRI® Humidity
· The water bottle is located on the side of the device for easy refilling and control of the water level.
· Passive humidification system.

Mini MIRI® Dry
· Has a built-in gas mixer. Premixed gas is not required · Comes with a UV module and VOC/HEPA filter.

This equipment is a CE-marked device and is in conformity with the essential requirements of the medical devices EU regulation 2017/745.
General Specifications

Model

Mini MIRI® Dry

Mini MIRI® Humidity

Overall Dimensions (W x D x H)

525 x 420 x 230 mm (20.7 x 16.5 x 9.1″)

Chamber Dimensions

200 x 176 x 25 mm (7.9 x 6.9 x 1″)

Power Supply

115 / 230V, 50/60 Hz

Power Consumption

160 W

Temperature Control Range

24.9 ­ 40.0 °C

*CO2 Gas Consumption **N2 Gas Consumption
Input Gas Pressure

<2 L/h <8 L/h

0.4 ­ 0.6 bar (5.80 ­ 8.70 PSI)

< 4 L/h <12 L/h

CO2 Control Range O2 Control Range Net weight

1.9 ­ 9.9% 3.9 ­ 19.9% 22 kg (48.5 lbs)

Shipping weight

30 kg (66.1 lbs) (Including the pallet’s weight)

Shipping Dimensions

630 x 525 x 500 mm (24.8 x 20.7 x 19.7″) (device on the pallet)

Ordering Information

• Under normal condition (CO2 setpoint reached at 6.0%, all lids closed). ** Under normal condition (O2 setpoint reached at 5.0%, all lids closed).

ITEM CODE 2070155 2070156 2070143 2070144

MODEL CODE MRI-MINI-H-8 MRI-MINI-H-9 MRI-MINI-D-8 MRI-MINI-D-9

DESCRIPTION Mini MIRI® Humidity, 230V, 50/60Hz Mini MIRI® Humidity, 115V, 50/60Hz Mini MIRI® Dry, without Humidification, 230V, 50/60Hz Mini MIRI® Dry, without Humidification, 115V, 50/60Hz

11

Heating optimization plates for MIRI® family’s multiroom IVF incubators
Extensive list of the heating optimization plates for MIRI®, MIRI® II-12, and Mini MIRI®
When placing an order for MIRI®, MIRI® II-12 or Mini MIRI®, all you have to do is select the appropriate heating optimization plate(s) that match the dishes used in your laboratory. There are no limitations to the choice you make, giving you the freedom and flexibility to choose as per your requirements. The MIRI®, MIRI® II-12 and Mini MIRI® can easily be incorporated into your existing work routine.
All heating optimization plates are optimized for the direct transfer of heat to the dishes and are totally removable for easy cleaning. This is to ensure optimal conditions for your embryos.

NuncTM

Falcon®

Vitrolife

Ordering Information

ITEM CODE For MIRI® and Mini MIRI®
1320003 1320004 1320070 1320099 1320100 1320101 1320118 1320507 For MIRI® II-12 1320429 1320430 1320431 1320433 1320436 1320434 1320505

MODEL CODE
MRA-FD MRA-ND MRA-VD MRA-NID MRA-LD MRA-PD MRA-OD
BIRR
MRA2-FD MRA2-ND MRA2-VD MRA2-LD MRA2-OD MRA2-PD
BIRR

LifeGlobal®

BIRR

GPS Dishes

SparMED Oosafe®

DESCRIPTION
Insert for Falcon® Dishes Insert for NuncTM Dishes Insert for Vitrolife Dishes Insert for NiproTM Dishes Insert for LifeGlobal® GPS Dishes Insert Without Footprint for Plain Dishes Insert for SparMED Oosafe®
Insert for BIRR Dishes
Insert for Falcon® Dishes Insert for NuncTM Dishes Insert for Vitrolife Dishes Insert for LifeGlobal® GPS Dishes Insert for SparMED Oosafe®
Insert for Plain Dish Insert for BIRR Dishes

12

Quality Assurance and Validation Units

MIRI® GA Gas and Temperature Validation Unit
MIRI® GA is a tabletop device intended to make external incubator validation easier and safer. It is capable of monitoring the temperature (PT1000 connector) & gas concentration, flow and pressure. It can validate up to 6 chambers simultaneously 24 hours a day. It also has an adjustable flow rate which gives it the ability to properly sample small volume incubation chambers. Moreover, MIRI® GA comes with a full Data Logger software which is helpful in monitoring each parameter. The MIRI® GA can connect to any brand of incubator and is a perfect accessory to MIRI® TL and MIRI® Multiroom Incubators.

Key Features
· Constantly validate up to 6 x CO2 / O2 incubators.
· CO2 / O2 incubators controllable flow rate Monitor up to 6 x PT 1000 sensors.
General Specifications

· 6 ports for sequential gas samples. · Gas feedback returns sampled gas
to incubator or exhaust.

Input ports

6 x PT1000 ports for temerature monitoring 6 x gas sampling ports

Output ports Shipping dimensions and weight

1 x gas feedback port, 1 x USB port
440mm x 430mm x 240mm (17.3″ x 16.9″ x 9.4″), 15kg (33.1lbs)

Ordering Information*

ITEM CODE

MODEL CODE

DESCRIPTION

1320045

MRI-GA

MIRI® GA C1O125//2O320/VT,e5m0p/6v0aHlizdation Unit,

*Includes data logger software, 1pc PT1000 cable, 1pc Gas connection tube, 1pc Gas feedback tube

Accessories
ITEM CODE 1320063 1320064 1320065 1320066

MODEL CODE MRA-1101 MRA-1102 MRA-1103 MRA-1104

DESCRIPTION 1pc PT1000 cable Set of 6pcs PT1000 cables 1pc Gas connection tube Set of 6pcs Gas connection tubes

13

ESCO LIFESCIENCES GROUP

Global Offices
Licensee Distributors Factories R&D Centers Regional Distribution Centers

Esco Medical Products

MIRI® Multiroom Incubator MIRI® Humidity Multiroom Incubator MIRI® II-12 Multiroom Incubator Mini MIRI® Dry Incubator Mini MIRI® Humidity Incubator MIRI® TL6 Time-Lapse Incubator MIRI® TL12 Time-Lapse Incubator Multi-Zone ART Workstation Airstream® Laminar Flow Bench

MIRI® Evidence RFID Traceability System CelCulture® CO2 Incubator MIRI® GA (Gas and Temperature Validation Unit) MIRI® AVT CultureCoin®

Infertility is a problem that has a significant social, psychological, and economic impact on afflicted individuals and couples. It is a global concern that knows no race or creed. It has been estimated that 1 in 6 couples struggle with infertility at least once in their lifetime.
Esco Medical is one of the divisions of the Esco Lifesciences Group. We provide innovative technological solutions for fertility clinics and laboratories. We aim to become the leading manufacturer of high-quality equipment such as long-term embryo incubators, ART workstations, anti- vibration tables, and time-lapse incubators.
Our products are designed with the Silent Embryo Hypothesis as a guiding principle. The Silent Embryo Hypothesis states that the less disturbed an embryo can remain, the better its developmental potential will be. Most of our products are designed in Denmark and made in the EU. Our primary focus is to increase pregnancy success rates and patient satisfaction.

21 Changi South Street 1 · Singapore 486 777 Tel +65 6542 0833 · medical@escolifesciences.com www.esco-medical.com
Esco Global Offices: Bangladesh | China | Denmark | Germany | Hong Kong | Indonesia | Lithuania | Malaysia | Myanmar | Philippines | Russia | Singapore | South Africa | South Korea | Taiwan | Thailand | UAE | UK | USA | Vietnam

Designed in Denmark

Made in the E.U.

13485

9010540_MIRI Incubators Combined Catalogue_A5_vJ_050824 Esco can accept no responsibility for possible errors in catalogues, brochures and other printed materials. Esco reserves the right to alter its products and specifications without notice. All trademarks and logotypes in this material are the property of Esco and the respective companies.

CERT NO.: 2020-1-1036 ISO 9001 : 2015

QS-2001-11

CERT NO.: 2020-0823 ISO 14001 : 2015

ES-2016-02

CERT NO: Q5 083797 0007 Rev. 00 EN ISO 13485 : 2016

D-ZM-11321-01-00

CERT NO: QS2 083797 0008 Rev. 00 ISO 13485 : 2016

CERT NO: QS2 064589 0008 Rev. 01 ISO 13485 : 2016

CERT NO.: 2020-2-2592 ISO 9001 : 2015

QS-2001-11

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