thermo scientific ImmunoCAP IgE Testing User Guide

thermo scientific ImmunoCAP IgE Testing

Get a clearer picture of your patients’ suspected allergy symptoms
Ready to get a clearer picture of your patient’s allergy triggers? This quick guide will show you how to get started. See how to confidently select, interpret, and apply ImmunoCAP™ Specific IgE blood tests for respiratory symptoms.

When to consider ImmunoCAP Specific IgE tests

Identify appropriate patients

• Look for patients with symptoms and a history of rhinitis, nasal congestion, rhinorrhea, sneezing, coughing, wheezing, chest tightness and/or shortness of breath
• These symptoms can indicate the patient is suitable for ImmunoCAP Specific IgE blood testing for respiratory allergens (tree-, grass- and weed pollen, dust mites, molds, cat and dog dander, mouse urine, and cockroach)

How to proceed

• Select allergens according to your patient’s symptoms and history
• Most laboratories offer ImmunoCAP Specific IgE blood testing to support the diagnosis of allergies
• Reach out to your partner laboratory for detailed information

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Still not sure how to order? Get in touch and we will connect you with a representative who can help.

How to interpret results

Initial interpretation steps:

• Combine ImmunoCAP Specific IgE blood test results with the patient’s history, symptoms, and physical exam findings to inform your understanding and decision-making3,4

Use the test results applicable only to respiratory allergen result interpretation:

• The results indicate the patient’s level of sensitization to specific allergens, measured in kilounits of allergen-specific IgE antibodies per liter of blood (kUA/l)2
• Utilize our test interpretation guides to confidently identify and manage allergies

Management considerations

• Consider other causes
• A negative result for a suspected allergen sensitization still aids in patient care
• Negative results help eliminate unnecessary allergen avoidance or ineffective anti-allergic medications, like antihistamines4
• Categorise results ranked from highest to lowest specific IgE sensitizations
• Provide allergen avoidance plan to keep the patient below the symptom threshold4
  • Reduce exposure to allergens related to the patient’s symptoms first
  • Focus on indoor allergens since these may be easier to control
• Prescribe appropriate medication if needed, e.g. antihistamines4
• Consider referral to specialists for a decision on allergen immunotherapy (AIT)4

In conclusion
Complementing patient history, symptoms, and physical exams with a specific IgE blood test helps to get a clearer picture of your patient’s suspected allergies. Specific IgE blood testing can help unlock the full story.

Consider ImmunoCAP Specific IgE blood testing for your patients with respiratory symptoms. Reach out to your partner laboratory for detailed information on ImmunoCAP Specific IgE testing.

References

1. Dykewicz MS et al. (2020) Rhinitis 2020: a practice parameter update. J Allergy Clin Immunol. 146(4):721–767.
2. ImmunoCAP™ Specific IgE Conjugate 400 Directions for Use. Published 2022-06-02. 3. Demoly P, Liu AH, Rodriguez Del Rio P, Pedersen S, Casale TB, Price D (2022) A pragmatic primary practice approach to using specific IgE in allergy testing in asthma diagnosis, management, and referral. J Asthma Allergy. 15:1069–1080. 4. Papadopoulos NG et al. (2015) Phenotypes and endotypes of rhinitis and their impact on management: a PRACTALL report. Allergy. 70(5):474–494.
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Specifications

• Product Name : ImmunoCAP Specific IgE Testing Kit
• Usage : For identifying specific IgE antibodies in blood related to respiratory allergens
• Manufacturer : ImmunoDiagnostics
• Storage: Store at the recommended temperature indicated on the kit

Frequently Asked Questions (FAQ)

Q: How should I store the ImmunoCAP Specific IgE Testing Kit?
A: The kit should be stored at the temperature recommended on the packaging to maintain its effectiveness.

Q: Can this test be used for non-respiratory allergens?
A: The ImmunoCAP Specific IgE test is designed specifically for respiratory allergens and should be interpreted accordingly.

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