thermoscientific 50155007 Cell Locker User Manual

thermoscientific 50155007 Cell Locker

The Cell Locker 50155007 is a product manufactured by Thermo Fisher Scientific. It is intended for use in laboratories and research facilities to store samples that do not contain hazardous chemical substances. The product is not for use in medical devices.

General Notes

The instruction manual provides safety information and symbols to indicate hazardous situations that could result in death, serious injuries, minor or moderate injuries, or damage to equipment or property. Special attention must be paid to the information given in the instruction manual or accompanying documents.

Explanation of Safety Information and Symbols

• Warning: Indicates a hazardous situation that, if not avoided, could result in death or serious injuries.
• Caution: Indicates a hazardous situation which, if not avoided, could result in minor or moderate injuries.
• Notice: Indicates a situation which, if not avoided, could result in damage to equipment or property.

Icons are used for application hints and useful information. The harmful liquids, fire hazards, and toxic substances, wear safety gloves, wear safety goggles, and wear breathing protection icons denote specific safety precautions that should be taken when using the product.

Safety Notes

Users should observe the sample weight limits as a whole and its shelving in particular. The door seal should be checked every six months for proper sealing performance and possible damage. Samples containing hazardous chemical substances that may be released into the ambient air through defective seals or may cause corrosion or other defects should not be processed.

Warranty

The product comes with a warranty, the details of which are not provided in the instruction manual. Users should refer to the accompanying documents for warranty information.

Delivery of the Device

The scope of delivery includes the Cell Locker 50155007 and its accompanying documents.

Acceptance Inspection

Users should inspect the product upon delivery for any damage that may have occurred during shipping. If damage is found, the user should contact Thermo Fisher Scientific immediately to report the damage.

Service

The instruction manual provides information on membrane filter replacement and cover gasket replacement. Users should follow the instructions carefully when replacing these parts.

Spare and Wear Parts

The instruction manual provides information on spare and worn parts for the Cell Locker 50155007.

Disposal

The instruction manual provides information on the proper disposal of the product and its components. Users should follow local regulations for disposal.

Technical Data

The instruction manual provides technical data on the Cell Locker 50155007, including its dimensions, weight, power requirements, and operating conditions.

Product Usage Instructions

When using the Cell Locker 50155007:

• Observe the sample weight limits as a whole and its shelving in particular.
• Check the door seal every six months for proper sealing performance and possible damage.
• Do not process any samples containing hazardous chemical substances that may be released into the ambient air through defective seals or may cause corrosion or other defects.
• Follow the instructions provided in the manual when replacing membrane filters or cover gaskets.
• Refer to local regulations for proper disposal of the product and its components.

Preface
© 2021 Thermo Fisher Scientific Inc. All rights reserved.
Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to use in the product operation. This document is copyright protected and any reproduction of the whole or any part of this document is strictly prohibited, except with the written authorization of Thermo Fisher Scientific Inc.
The contents of this document are subject to change without notice.
Thermo Fisher Scientific Inc. makes no representations that this document is complete, accurate or error-free and assumes no responsibility and will not be liable for any errors, omissions, damage or loss that might result from any use of this document, even if the information in the document is followed properly.
This document is not part of any sales contract between Thermo Fisher Scientific Inc. and a purchaser. This document shall in no way govern or modify any Terms and Conditions.
In case of conflicting translations into foreign languages the German-language version of these operating instructions shall be binding.

General notes

Explanation of safety information and symbols

Warning

• Indicates a hazardous situation which, if not avoided, could result in death or serious injuries.

Caution

• Indicates a hazardous situation which, if not avoided, could result in minor or moderate injuries.

Notice

• Indicates a situation which, if not avoided, could result in damage to equipment or property.

Safety notes

• The CELL LOCKER may only be used by instructed personnel.
• The present operating instructions, applicable safety data sheets, hygiene guidelines and the corresponding technical rules issued by the operator shall be used to create written procedures targeted at personnel working with the subject matter device, detailing:
• the decontamination measures to be employed for the CELL LOCKER and the accessories used with it,
• the safety precautions to be taken when processing specific agents,
• wearing protective equipment when handling e.g. microbiological and biological samples,
• the measures to be taken in case of accidents,
• drying time after decommissioning, as Transport 2 hours,
• working according to GLP – Good Laboratory Practice.

Operational Safety Rules

• Observe the sample weight limits as a whole and its shelving in particular.
• Check the door seal every six months for proper sealing performance and possible damage.
• Do not process any samples containing hazardous chemical substances that may be released into the ambient air through defective seals or may cause corrosion or other defects.

Warranty

• Thermo Fisher Scientific warrants the operational safety and functions of the CELL LOCKER for one year only under the condition that:
• the CELL LOCKER is operated and serviced exclusively in accordance with its intended purpose and as described in these operating instructions,
• the device is not modified,
• only original spare parts and accessories that have been approved by Thermo Fisher Scientific are used (third-party spares without Thermo Fisher Scientific approval void the limited warranty),
• inspections and maintenance are performed at the specified intervals,
• an operation verification test is performed after each repair activity.
• The warranty is valid from the date of delivery of the CELL LOCKER to the customer.

Intended Purpose

Correct Use

• The CELL LOCKER is intended for use in laboratory equipment, which among others is used for the preparation and cultivation of cell and tissue cultures for research applications.
• The maximum Autoclave temperature is 15 minutes at 121°C (250 °F) with fast exhaust.

Incorrect Use

• Do not use tissues, substances or liquids that:
• are easily flammable or explosive;
• release vapor or dust that forms combustible or explosive mixtures when exposed to air;
• release poisons;
• release dust;
• exhibit exothermic reactions;
• are pyrotechnical substances.
• Do not pour any liquids on the bottom of the interior surface or into a collecting basin inside the unit.
• The CELL LOCKER is not for use in Medical Devices.

Delivery of the device

Scope of delivery

Acceptance inspection

After the CELL LOCKER has been delivered, check the delivery immediately for:

• completeness,
• possible damage.
• If components are missing or damage is found on the device or the packaging, please contact the carrier, as well as the customer service, immediately.

Description of the device

Description

• The CELL LOCKER consists of a polycarbonate chamber with two membrane filters, which are permeable to water vapor and gas, but are impermeable to microorganisms.

First use

When using the first time, clean and disinfect the CELL LOCKER.

Note

• Clean the CELL LOCKER before inserting the membrane frame with filter.

Warning

• The CELL LOCKER must be removed before the incubator is sterilized.

Operation

• The CELL LOCKER can be placed into the incubator with 6-door gas tight screen with or without cover.
• When inserting into a laboratory device make sure that the CELL LOCKER is not twisted.

Application versions

• Depending on user preference, the CELL LOCKER can be modified to attach or remove the transport cover, using the consumables kit:
• Cover can be attached to work tray with the Allen key, allowing protected transport.
• Note: Attach cover for protected transport to biosafety cabinet or to another incubator or lab. Use of cover in the chamber may require two hand opening.

Cleaning and disinfection

• Before starting any work, the following safety hints should be followed:

Warning

• Health hazard!
• The surfaces of the work space may be contaminated. Contact with contaminated cleaning liquids may cause infections. Disinfectants may contain harmful substances. When cleaning and disinfecting, always observe the safety instructions and hygiene guidelines.
• Wear safety goggles!
• Wear safety gloves!
• Wear breathing protection!
• Observe the safety instructions of the disinfectant‘s manufacturer and the hygiene supervisor!

Cleaning

Caution

• Incompatible cleaners!
• Some of the CELL LOCKER components are made of plastic.
• Solvents may attack plastics.
• Strong acids or alkaline solutions may cause corrosion of plastics.

Caution

• Moisture-sensitive components!
• Do not spray cleaning agent onto the membrane filter of the CELL LOCKER. When wiping the membrane filter frame make sure that no moisture contacts the membrane filter.
• Remove dirt residues and deposit thoroughly using a solution of lukewarm water and mild detergent.
• Wipe the surfaces and work plate with a clean cloth and clear water. Then, wipe the surfaces dry using a clean cloth.

Wipe/spray disinfection

Caution

• Alcoholic disinfectants!
• Disinfectants having a alcohol content of more than 10% may form, in combination with air, easily combustible and explosive gas mixtures.
• When using such disinfectants, avoid open flames or exposure to excessive heat during the entire disinfection process.
• Use such disinfectants only in adequately ventilated rooms.
• After the disinfectant has been allowed to react, wipe the cleaned CELL LOCKER components thoroughly dry.
• Observe safety regulations to avoid fire and/or explosion hazard caused by alcohol-containing disinfectants.

Caution

• Chloride-containing disinfectants!
• Do not use chloride-containing disinfectants.
• Use only disinfectants that do not affect stainless steel.

Warning

• Decontamination or cleaning agents!
• Thermo Electron LED GmbH or his agent is to be consulted, if there is any doubt about the compatibility of decontamination or cleaning agents.

1. Remove all samples from the work space and store them in a safe place.
2. Spray disinfectant onto the surfaces of the work space and of the accessories or wipe the surfaces clean using disinfectant. Do not spray disinfectant onto the membrane filters.
3. Allow time for the disinfectant to act as specified by the manufacturer.
4. Wipe off the chamber surfaces and the work tray using lukewarm water mixed with standard rinsing agents. Rinse completely using warm water.
5. Re-rinse the cleansed surfaces 3 to 5 times with autoclaved water to completely remove any cleaning agent residues.
6. After this, wipe the cleansed surfaces, air baffle and internals dry with a soft, sterile cloth.

Autoclaving
The CELL LOCKER can be autoclaved up to 15 minutes at 121°C with fast exhaust. Autoclaving at higher temperature is not recommended since the material cannot withstand higher temperature and its composition would be negatively affected.
Note
Remove the membrane frame with filter before autoclaving the CELL LOCKER.

Service

Any service work should be recorded.
Membrane filter replacement
Periodically check the membrane frame filters and at least once a year replace them.

Warning  Health hazard!

• Wear safety gloves!
• Wear breathing protection!

1. Pull out the work tray and take it out.
2. Press and remove the membrane frame from the inside.
3. Put the membranes into a plastic bag, autoclave them and dispose as hazardous waste.
4. Unpack the new membranes.
5. Insert the new membrane frame and press firmly in the radial direction.
6. Visually inspect from the inside, whether the gasket lip is correctly seated, if necessary press from the outside.
7. Insert the second membrane according to 5. and 6.
   • Warning Contamination hazard!
   • Damaged or improperly mounted membranes can contaminate the user or the environment!
8. Insert the work tray over the tilting stop and push into the interior.

Cover gasket replacement

Inspect the cover gasket periodically, e.g. monthly, for integrity, no damage and replace as needed.

1. Pull out the work tray and take it out.
2. Remove cover gasket from the notch.
3. Insert a new gasket in the notch and take care that the gasket lip is outside.
   • Warning Contamination hazard!
   • Damaged or improperly mounted membranes can contaminate the user or the environment!
4. Insert the work tray and push into the interior.

Spare and wear parts

Only original spare parts and accessories that have been approved by Thermo Fisher Scientific used, third-party spares without Thermo Fisher Scientific approval void the limited warranty.

Disposal

Warning

• Contamination hazard!
• The device may have been used for treating and processing infectious substances. Therefore, the device and device components may have been contaminated. Prior to disposal, all device components must be decontaminated!
• Clean the unit components thoroughly, then disinfect,decontaminate or autoclave them (depending on application).
• Attach a declaration of non-objection with details of performed decontamination measures to the items that are to be disposed of.
• All device components can be disposed of after they have been decontaminated properly. Membrane filters must be disposed of in accordance with applicable national legislation and directives on the handling of hazardous waste.

Overview of the materials used

Technical Data

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