CARVYKTI Risk Evaluation Mitigation strategy Instructions

September 26, 2024
CARVYKTI

Risk Evaluation Mitigation strategy

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Product Information

Specifications

Product Usage Instructions

Hospital Enrollment Form

In order to dispense CARVYKTI, Hospitals and their Associated
Clinics must be certified in the CARVYKTI REMS and have on-site
immediate access to tocilizumab. Hospitals and their Associated
Clinics must designate an Authorized Representative to:

Hospitals and Associated Clinics Information

Complete the following fields:

  • Hospital and Associated Clinics Name
  • REMS ID
  • Address
  • City
  • State
  • Zip Code
  • Phone
  • Fax

Authorized Representative Information

Complete the following fields:

  • First Name
  • Last Name
  • Credentials (DO, MD, R.Ph, NP/PA, RN, Other)
  • Phone
  • Fax
  • Email

Authorized Representative Responsibilities

The Authorized Representative is responsible for overseeing
implementation and coordinating activities of the CARVYKTI REMS. By
signing the form, the Authorized Representative agrees to comply
with all REMS Requirements.

FAQ

Q: Where can I find additional information about CARVYKTI

REMS?

A: For any questions or additional information, please visit the
REMS website at www.CARVYKTIREMS.com or call the
CARVYKTI REMS Coordinating Center at 1-844-672-0067.

Q: What are the responsibilities of the Authorized

Representative?

A: The Authorized Representative is designated to ensure
compliance with all REMS requirements and oversee implementation of
the CARVYKTI REMS within the Hospital and Associated Clinics.

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CARVYKTI® RISK EVALUATION MITIGATION STRATEGY (REMS)
Hospital Enrollment Form

Phone: 1-844-672-0067 Fax: 1-877-778-3865 E-mail: CARVYKTI@JanssenREMS.com www.CARVYKTIREMS.com

Instructions
CARVYKTI® (ciltacabtagene autoleucel) is only available through the CARVYKTI Risk Evaluation and Mitigation Strategy (REMS).
In order to dispense CARVYKTI, Hospitals and their Associated Clinics must be certified in the CARVYKTI REMS and have on-site immediate access to tocilizumab (the “Hospitals and their Associated Clinics”). Hospitals and their Associated Clinics must designate an Authorized Representative to:
· Complete the certification process by completing the Hospital Enrollment Form on behalf of the Hospital and Associated Clinics.
· Oversee implementation and compliance with the CARVYKTI REMS requirements as outlined below.
To comply:
· Please complete all required fields below and submit this enrollment form to the REMS Coordinating Center via fax to 1-877-778-3865, e-mail at CARVYKTI@JanssenREMS.com or complete it online at www.CARVYKTIREMS.com. You will receive a confirmation via e-mail.
· Completion of this form does not guarantee your Hospital and Associated Clinics will be certified to administer CARVYKTI.
· The CARVYKTI REMS will assess and provide confirmation of certification via e-mail after processing this enrollment form.
· Product orders cannot be placed until the Hospital and Associated Clinics certification is complete.
If you have any questions, require additional information, or need further copies of any of the CARVYKTI REMS materials, please visit the REMS website at www.CARVYKTIREMS.com or call the CARVYKTI REMS Coordinating Center at 1-844-672-0067.

Hospitals and Associated Clinics Information (All Fields Required)
New Certification Change in Authorized Representative Hospital and Associated Clinics Name:

Hospital and Associated Clinics REMS ID:

Address:

City:

State:

Zip Code:

Phone:

(XXX) XXX-XXXX

Fax:

(XXX) XXX-XXXX

Authorized Representative Information (All Fields Required)

First Name:

Last Name:

Credentials:

DO MD R.Ph NP/PA RN Other (please specify)

Phone:

(XXX) XXX-XXXX

Fax:

(XXX) XXX-XXXX

e-mail:

Authorized Representative Signature

Date (MM/DD/YYYY)

March2024

CARVYKTI® RISK EVALUATION MITIGATION STRATEGY (REMS)
Hospital Enrollment Form
Authorized Representative Responsibilities
On behalf of my Hospital and Associated Clinics, I am the Authorized Representative, designated by my Hospital and Associated Clinics, to oversee implementation and coordinate the activities of the CARVYKTI REMS. By signing this form, I agree, on behalf of myself and my Hospital and Associated Clinics, to comply with all REMS Requirements. I will:
· Complete the Hospital Enrollment Form. · Submit the Hospital Enrollment Form to the REMS Coordinating Center via fax to 1-877-778-3865, e-mail at CARVYKTI@JanssenREMS.com, or complete it online at www.CARVYKTIREMS.com.
· Oversee implementation and compliance with the CARVYKTI REMS. · Ensure that my Hospital and Associated Clinics establishes processes and procedures that are subject to monitoring by
Janssen Biotech, Inc, or a third party acting on behalf of Janssen Biotech, Inc to ensure compliance with the requirements of the CARVYKTI REMS, including the following, before administering CARVYKTI: a. Prior to dispensing CARVYKTI, put processes and procedures in place to verify on-site, immediate access to at least
two doses of tocilizumab for each patient, for administration within two hours after infusion. As a condition of certification, the Hospital and Associated Clinics shall: · Ensure that if the Hospital and Associated Clinics designate a new Authorized Representative, the new Authorized
Representative must complete a new Hospital Enrollment Form and submit the form via fax to 1-877-778-3865, e-mail at CARVYKTI@JanssenREMS.com or complete it online at www.CARVYKTIREMS.com. · At all times, staff should report suspected adverse events or product quality complaints to Janssen at 1-800-Janssen (1-800-526-7736) or the FDA at 1-800-FDA-1088 or online at www.fda.gov/medwatch. · Dispense CARVYKTI to patients only after verifying on-site, immediate access to at least two doses of tocilizumab for each patient, for administration within 2 hours after infusion. · Maintain documentation of all processes and procedures for the CARVYKTI REMS and provide documentation upon request by Janssen Biotech, Inc or third party acting on behalf of Janssen Biotech, Inc. · Comply with audits by Janssen Biotech, Inc, or a third party acting on behalf of Janssen Biotech, Inc.
March2024

References

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