NARCAN Naloxone HCL Nasal Spray User Guide

NARCAN Naloxone HCL Nasal Spray

Use NARCAN® (naloxone hydrochloride) Nasal Spray for known or suspected opioid overdose in adults and children. Important: For use in the nose only. Do not remove or test the NARCAN® Nasal Spray until ready to use.

Identify Opioid Overdose and Check for Response

Ask person if he or she is okay and shout name. Shake shoulders and firmly rub the middle of their chest. Check for signs of an opioid overdose:

• Will not wake up or respond to your voice or touch
• Breathing is very slow, irregular, or has stopped
• Center part of their eye is very small, sometimes called “pinpoint pupils” Lay the person on their back to receive a dose of NARCAN® Nasal Spray.

Give NARCAN® Nasal Spray

• REMOVE NARCAN® Nasal Spray from the box. Peel back the tab with the circle to open the NARCAN® Nasal Spray. Hold the NARCAN® Nasal Spray with your thumb on the bottom of the red plunger and your first and middle fingers on either side of the nozzle.
• Gently insert the tip of the nozzle into either nostril.
• Tilt the person’s head back and provide support under the neck with your hand. Gently insert the tip of the nozzle into one nostril, until your fingers on either side of the nozzle are against the bottom of the person’s nose
• Press the red plunger firmly to give the dose of NARCAN® Nasal Spray.
• Remove the NARCAN® Nasal Spray from the nostril after giving the dose

Call for Emergency Medical Help, Evaluate, and Support

Get emergency medical help right away. Move the person on their side (recovery position) after giving NARCAN® Nasal Spray. Watch the person closely. If the person does not respond by waking up, to voice or touch, or breathing normally, another dose may be given. NARCAN® Nasal Spray may be dosed every 2 to 3 minutes, if available. Repeat Step 2 using a new NARCAN® Nasal Spray to give another dose in the other nostril. If additional NARCAN® Nasal Sprays are available, repeat step 2 every 2 to  3 minutes until the person responds or emergency medical help is received.

INDICATION AND IMPORTANT SAFETY INFORMATION

• NARCAN® Nasal Spray is a prescription medicine used for the treatment of a known or suspected opioid overdose emergency with signs of breathing problems and severe sleepiness or not being able to respond.

• NARCAN® Nasal Spray is to be given right away and does not take the place of emergency medical care. Get emergency medical help right away after giving the first dose of NARCAN® Nasal Spray, even if the person wakes up.

• NARCAN® Nasal Spray is safe and effective in children for known or suspected opioid overdose.

• Do not use NARCAN® Nasal Spray if you are allergic to naloxone hydrochloride or any of the ingredients in NARCAN® Nasal Spray.

• What is the most important information I should know about NARCAN® Nasal Spray?
  NARCAN® Nasal Spray is used to temporarily reverse the effects of opioid medicines. The medicine in NARCAN® Nasal Spray has no effect in people who are not taking opioid medicines. Always carry NARCAN® Nasal Spray with you in case of an opioid overdose.

• Use NARCAN® Nasal Spray right away if you or your caregiver think signs or symptoms of an opioid overdose are present, even if you are not sure, because an opioid overdose can cause severe injury or death.

• Signs and symptoms of an opioid overdose may include: unusual sleepiness and you are not able to awaken the person with a loud voice or by rubbing firmly on the middle of their chest (sternum); breathing problems including slow or shallow breathing in someone difficult to awaken or who looks like they are not breathing; the black circle in the center of the colored part of the eye (pupil) is very small, sometimes called “pinpoint pupils,” in someone difficult to awaken

• Family members, caregivers, or other people who may have to use NARCAN® Nasal Spray in an opioid emergency should know where NARCAN® Nasal Spray is stored and how to give NARCAN® before an opioid emergency happens.

• Get emergency medical help right away after giving the first dose of NARCAN® Nasal Spray. Rescue breathing or CPR (cardiopulmonary resuscitation) may be given while waiting for emergency medical help.

• The signs and symptoms of an opioid overdose can return after NARCAN®

• A nasal Spray is given. If this happens, give another dose after 2 to 3 minutes using a new NARCAN® Nasal Spray and watch the person closely until emergency help is received.

• What should I tell my healthcare provider before using NARCAN® Nasal Spray?
  Before using NARCAN® Nasal Spray, tell your healthcare provider about all of your medical conditions, including if you: have heart problems; are pregnant or plan to become pregnant. Use of NARCAN® Nasal Spray may cause withdrawal symptoms in your unborn baby. Your unborn baby should be examined by a healthcare provider right away after you use NARCAN® Nasal Spray; are breastfeeding or plan to breastfeed. It is not known if NARCAN® Nasal Spray passes into your breast milk.

• Tell your healthcare provider about the medicines you take, including prescription and over-the-counter medicines, drugs, vitamins, and herbal supplements.

• What are the possible side effects of NARCAN Nasal Spray?
  NARCAN® Nasal Spray may cause serious side effects, including sudden opioid withdrawal symptoms which can be severe. In someone who has been using opioids regularly, opioid withdrawal symptoms can happen suddenly after receiving NARCAN® Nasal Spray and may include: body aches, diarrhea, increased heart rate, fever, runny nose, sneezing, goose bumps, sweating, yawning, nausea or vomiting, nervousness, restlessness or irritability, shivering or trembling, stomach cramping, weakness, increased blood pressure.

• Some patients may show aggressive behavior upon abrupt reversal of an opioid overdose.

• In infants under 4 weeks old who have been receiving opioids regularly, sudden opioid withdrawal may be life-threatening if not treated the right way. Signs and symptoms include seizures, crying more than usual, and increased reflexes.

• These are not all of the possible side effects of NARCAN® Nasal Spray. Call your doctor for medical advice about side effects.You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

NNS CON ISI 08/2020
CLICK HERE FOR FULL PRESCRIBING INFORMATION

ABOUT COMPANY

© 2022 Emergent Devices Inc. Plymouth Meeting, PA. All rights reserved. NARCAN® is a registered trademark of Emergent Operations Ireland Limited. Emergent devises Inc. and Emergent Operations Ireland Limited are wholly-owned subsidiaries of Emergent BioSolutions Inc. PP-NAR4-US-00581 02/2022

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