REGENSIFY DHT Blocking Shampoo 500 ml (17 FL Oz) [Adenosine Shampoo Instructions

June 5, 2024
REGENSIFY

DHT Blocking Shampoo 500 ml (17 FL Oz) [Adenosine Shampoo
Instructions

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DHT Blocking Shampoo 500 ml
An Adenosine Shampoo with Biotin & DHT Blockers

ACTIVE INGREDIENTS:

Saw Palmetto Extract, Ecklonia Cava Extract, Biotin, Adenosine
INGREDIENTS:
Purified Water, Sodium Laureth Sulfate, Cocamidopropyl Betaine, Cocamide DEA, Polyquaternium 7, Propylene Glycol, Glycerin, DMDM Hydantoin, Fragrance, Biotin, Aloe Barbadensis, Iodopropynyl Butylcarbamate, Saw Palmetto Extract, Ecklonia Cava Extract, Tetrasodium EDTA, Adenosine

DESCRIPTION:

The DHT Blocking Shampoo regenerates the scalp conditions with clinically proven ingredients that block DHT and stimulate the hair follicles to grow. Saw Palmetto and Ecklonia Cava Extracts block DHT, the root cause of hair loss. Adenosine stimulates hair growth by boosting ATP production while Biotin rejuvenates hair health for improved hair quality. The shampoo cleanses and nourishes the scalp by unblocking dirt and oil in hair follicles, thus restoring the hair’s elasticity and strength.

DIRECTIONS:

Dispense the desired amount onto palms to form a rich lather. Apply to wet hair and gently massage over the entire scalp. Leave the shampoo on your hair and scalp for a period of 3-5 minutes to allow maximum absorption of the ingredients. Then, completely rinse the Shampoo from your scalp and hair using warm water. After the shampooing, it is recommended to use our Hair Regrowth Conditioner for best results.
Hair Regrowth Conditioner 500 ml
An Adenosine & Coenzyme Q10 Conditioner with Biotin & DHT Blockers
ACTIVE INGREDIENTS:
Saw Palmetto Extract, Ecklonia Cava Extract, Biotin, Adenosine, Ubiquinone (CoQ10)
INGREDIENTS:
Purified Water, Dimethicone, Coco Nucifera (Coconut) Oil, Cetrimonium Chloride, Cetyl Alcohol, Cetearyl Alcohol, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Polyquaternium 7, Propylene Glycol, Glycerin, Jasminum Officinale (Jasmine) Oil, Lavandula Angustifolia (Lavender) Oil, DMDM Hydantoin, Biotin, Iodopropynyl Butylcarbamate, Tetrasodium EDTA, Saw Palmetto Extract, Ecklonia Cava Extract, Ubiquinone, Adenosine
DESCRIPTION:
When combined with our DHT Blocking Shampoo, the Hair Regrowth Conditioner yields the most effective combination for combating hair loss. Saw Palmetto and Ecklonia Cava Extracts block DHT, the root cause of hair loss while Biotin rejuvenates hair health for improved hair quality. Adenosine and Coenzyme Q10 work synergistically by boosting and facilitating ATP production to stimulate hair growth. The Hair Regrowth Conditioner not only helps with the appearance of thinning hair but also helps to combat split ends and encourage thicker and voluminous hair.
DIRECTIONS:
We recommend using the Conditioner right after using our DHT Blocking Shampoo. Dispense a generous amount of the conditioner to your hair and scalp, including your hair ends. Leave the Conditioner on your hair and scalp for 3-5 minutes to allow maximum absorption of the ingredients. Then rinse it out with cold water. Dry off hair with a microfiber towel.
Identifying Hair Regrowth Serum 60 ml
Enhanced with Adenosine, Biotin, Coenzyme Q10, Centella Asiatica, and DHT Blockers, the Redensifying Hair Regrowth serum is the ultimate Redensyl therapy formulation for hair restoration.
ACTIVE INGREDIENTS:
Redensyl, Saw Palmetto Extract, Ecklonia Cava Extract, Centella Asiatica Extract, Biotin, Adenosine, Ubiquinone (CoQ10)
INGREDIENTS:
Purified Water, Propylene Glycol, Alcohol Denatured, Polysorbate 20, Glycerin, Sodium Metabisulfite, Glycine, Larix Europaea Wood Extract, Zinc Chloride, Camellia Sinensis Leaf Extract, Ethylene Glycol Monophenyl Ether, Aloe Barbadensis, Saw Palmetto Extract, Ecklonia Cava Extract, Biotin, Ubiquinone, Centella Asiatica Extract, Sodium Gluconate, Allantoin, Citrus Oil, Orange Oil, Lavandula Angustifolia (Lavender) Oil, Pelargonium Graveolens (Geranium) Oil, Adenosine
DESCRIPTION:
The Redensifying Hair Regrowth Serum is a powerful serum formulated to address hair loss issues by identifying hair for thicker and healthier growth. The serum features an award-winning patented ingredient Redensyl®, clinically proven to activate the proliferation of hair follicle stem cells and to boost the metabolism of derma papilla fibroblasts. Saw Palmetto and Ecklonia Cava Extracts block DHT, the root cause of hair loss while Biotin rejuvenates hair health for improved hair quality. Adenosine and Coenzyme Q10 work by boosting and facilitating ATP production to stimulate hair growth. Centella Asiatica Extract, known for its superior healing properties, also nourishes and moisturizes the scalp while strengthening the hair follicles.
DIRECTIONS:
Apply directly onto clean, dry scalp, especially in hair thinning areas. Gently massage the scalp with fingertips. For best results, use two times a day with at least eight hours between each application. Do not rinse any water and leave the serum on the scalp for at least four hours for maximum absorption. In case of accidental contact with eyes, rinse eyes thoroughly with cold water. We recommend using the serum daily twice a day for at least four to six months continuously to see results.
Professional Bundle Set The Professional Bundle set comes with DHT Blocking Shampoo and Hair Regrowth Conditioner set at a super value deal. Healthy scalp begins with this Professional Bundle set.
Full Professional Bundle Set The Full Professional Bundle set comes with one set each of our DHT Blocking Shampoo, Hair Regrowth Conditioner and Redensifying Hair Regrowth serum at a super value deal. Complete your REGENSIFY haircare with this full professional bundle set in three steps.
Regrow Serum Bundle Set The Regrowth Serum Bundle set comes with 3 boxes of Redensifying Hair Regrowth serum at a super value deal. The perfect bundle you will need for your hair regrowth journey.
COMPLETE YOUR REEENSIF’7′ HRIRERRE IN THREE STEPS

An Adenosine Shampoo with Karin & DHT Blockers A super-premium grade formulation developed by REGENSIFY
An Adenosine & Coenzyme Q10 Conditioner with Biotin & DHT Blockers Formulated by REEENEI

Synergistically boosts & facilitates ATP production

Enhanced with Adenosine, Biotin, Coenzyme Q10, Centella Asiatica and DHT Blockers, the Redensifying Hair Regrowth serum is the ultimate Redensyl therapy formulation for hair restoration. Unique ABC Complex developed by REEENSIFY

The complex consists of adenosine, Biotin, and Coenzyme Q10, carefully optimized in ratio, to create a synergistic effect. Adenosine boosts ATP production while Coenzyme Q10 facilitates ATP production. Biotin is an essential vitamin for hair growth.

Contains various essential oils to nourish a healthy scalp

Active Ingredients

Below are lists of main active ingredients that we used in our haircare formulations. The list below does not include other inactive ingredients such as essential oils etc. Our formulations are paraben-free, synthetic fragrance- free, no artificial colorings, and cruelty-free. We used high-quality pharma- grade ingredients and worked with reputable cosmetics manufacturing companies in Singapore. All our products are manufactured in a GMP lab with stringent QC checks.
Hailed as the hair growth galvanizer, Reclensyl is a breakthrough hair growth stimulant that targets hair growth at the cellular level by activating the proliferation of hair follicle stem cells and boosting the metabolism of derma papilla fibroblasts. Redensyl is a synergistic blend of four active ingredients, consisting of Di hydroquercetin-glucoside (DHQG), Epigallocatechin gallate-glucoside (EGCG2), Glycine, and Zinc. The DHQG stimulates both the bulge stem cells and the derma papilla cells.
An extract of a Saw Palmetto berries is known to block 5-alpha-reductase, an enzyme that converts testosterone to DHT. DHT is the molecule responsible for hair loss. By reducing the effects of DHT, hair loss is reduced. Saw Palmetto is one of the best natural DHT blockers.
Ecklonia Cava is an edible brown seaweed harvested in the oceans around Jeju Island, South Korea. Rich in polyphenols, Ecklonia Cava is known for its antioxidant and anti-inflammatory properties. A South Korean study revealed that Ecklonia Cava promotes the growth of dermal papilla cells by increasing the size, depth and length of hair follicles as well as inhibits the similar levels of 5-alpha-reductase activity comparable to Finasteride. This makes Ecklonia Cava an excellent natural remedy that not only stimulates hair growth but also blocks off DHT to reduce hair loss.
Centella Asiatica (also known as Gotu Kola) is a herb that strengthens hair follicles while nourishing and moisturizing the hair scalp. Rich in phenols and flavonoids, TECA (Titrated Extract of Centella Asiatica) makes a superior healing agent on the skin due to its high antioxidant and anti-inflammatory properties. Gotu Kola is also thought to strengthen the pull strength of the hair, resulting in decreased hair loss.

ABC Complex is a proprietary complex developed by REGENSIFY

. The complex consists of Adenosine, Biotin and Coenzyme Q10, carefully optimized in ratio, to create a synergistic effect. Both Adenosine and Coenzyme Q10 are chemicals that your body produces naturally, which are essential for ATP to take place. However, as one age, the level of Adenosine and Coenzyme Q10 decreases, which results in a deficiency. Adenosine boosts ATP production while Coenzyme Q10 facilitates ATP production. Biotin is an essential nutrient in building that vital keratin infrastructure. The addition of this ABC complex helps address any hair loss due to nutrient deficiency, stress, or scalp aging.
Adenosine
Topical Adenosine is a hair growth stimulant that effectively boosts adenosine triphosphate (ATP) production on the hair scalp. Adenosine helps hair growth by increasing blood flow to the scalp. Various clinical studies in both men and women with AGA show that daily application of topical adenosine leads to significantly higher hair density and an increase in the proportion of thicker hairs.
Biotin (Also known as Vitamin B7)
Biotin, also known as vitamin B7, stimulates keratin production in hair and can increase the rate of follicle growth. Biotin is also an essential vitamin in supporting the normal function and growth of skin, hair, and nails. Biotin rejuvenates hair health for improved hair growth.
Coenzyme Q10 (Also known as Ubiquinone)
Coenzyme Q10 (also known as Ubiquinone or CoQ10) is a potent bioactive that stimulates the gene expression of different hair keratins, especially those which are reduced during aging processes in hair follicles. As such, CoQ10 has an anti-aging effect on hair health. As an antioxidant, CoQ10 also protects the hair cells against any harmful free radicals. CoQ10 facilitates the production of adenosine triphosphate (ATP) in the mitochondria by participating in redo): reactions within the electron transport chain,

Redensyl®: acts on stem cells and derma papilla
Extracted horn natural plant using patented manufacturing method, Redensylrr; is a breakthrough hair growth stimulant that targets hair growth at the cellular level by activating the proliferation of hair follicle stem cells and boosting the metabolism of derma papilla fibroblasts. Redensyl:; ii won the in-cosmetics 2014 Innovation Silver Award as the best cosmetic ingredient alternative to hair transplantation surgery

Redensyl®: The Hair Growth Galvaniser
Redensyliti Is a synergistic blend of four active Ingredients (Dihydroquercetin-glucoside (DHQG), Epigallocatechin gallate-glucoside (EGCG2), Glycine, and Zinc) that reactivate the bulge stem cells (ORS) and derma papilla (HFDPc) to stimulate hair growth.

  1. The DHQG molecule activates the a) division of hair follicle stern cells and allows stem cells to maintain their differentiation properties, b) protects the stem cells from apoptosis by driving them towards the anagen cycle, and c) boosts the metabolism of dermal papilla fibroblasts.
  2. The EGCG2 molecule reduces scalp inflammation.
  3. Glycine, a key amino acid for the hail, is essential for the growth of the hair shaft structure.
  4. Zinc, an essential for cystic incorporation into keratin, allows the strengthening of the hair shaft

Redensyl® acts like a switch. It wakes up hair stem cells.
In the early anagen phase, cells from the dermal papilla activate bulge stem cells, inducing new hair follicles to grow and replace the old hair that sheds. The bulge stern cells then self replicate and migrate into the matrix to create new active keratinocytes.
The derma papilla fibroblasts and epithelial stem cells need to communicate together in order to trigger the hair follicle’s cycle of growth. Otherwise, hair loss happens when the initiation of the new anagen phase (activation of ORS stem cells) is not activated.
Hence this is where Redensyl6r comes in to turn on hair growth, as RedensylC) targets both stern cells and derma papilla. Increase of hair follicle length (ex vivo Philpott test)
Redensyl4D was tested at 1% versus Minoxidil at 1% as a benchmark reference to evaluate its potential for hair follicle growth. Hairs of male donors suffering from alopecia were maintained alive In normal hair culture conditions. After 7 and 10 days, hair growth was measured compared to day 0 with pictures analysis.

Results: Redensyl® increases hair growth by +214% compared to untreated, and shows almost two times higher results than Minoxidil, the benchmark reference.
Redensyr: visible results after 3 months (clinical evaluation)
85% of volunteers show clinical improvements. More anagen hair, a higher density. more visible hair.
Examples of the clinical results of three volunteers (29 to 52 years old) treated with Reclensylw for 3 months.

Criteria| Volunteer #3 (52 years old)| Volunteer #6 (42 years old)| Volunteer

26 (29 years old)

---|---|---|---
3c of new anagen hair| +10.8%| + 19.2%| + 9.2%
% of the density of hair increase| +17%| + 17%| + T7%
Number of new hair; cm²| + 47hairi cm| + 43 hair J cm’| + 29 hair 1 crni
Total number of new hair on their scalp (600 cm’)| +28.200 hair| + 25.800 hair| +17,400 hair
Number of new hair per month on their scalp| +9,400 hair| + 8.600 hair| + 5.800 hair

Macro pictures (Phototnchograms)
Results: Hair looks thicker, with a visible improvement in density.
Scalp pictures
Results: Hair loss stopped, and a visible increase in hair density is noticeable.
Self-evaluation of RedensylTM (clinical)
A self-evaluation after 3 months was run by the volunteers.

Results: Testers claim Redensyr at 3% reduced their hair loss, improved the capillary density by strengthening and thickening their hair after three months of treatment
71% of the tters are satisfied by the product. and 71% of them would like to buy the product_
+10,200 hair in average in 3 months: better results than one hair transplantation procedure’.
Topical adenosine increases the proportion of thick hair in Caucasian men with androgenetic alopecia
Tokuro Iwabuchi 1, Ritsuro Meta 1, Ritsuko Ehama 1, Haruyo Yarnanishi 1, Masato lino 1 Yosuke Nakazawa 1, Takashi Kobayashi 2, Manabu Ohyama 3, Jiro Kishimoto 1
Affiliations expand
PMID: 26508659 DOI: 10.1111/1346-8138.13159
Abstract
Adenosine is an effective treatment for androgenetic alopecia (AGA) in Japanese men and women. Adenosine exerts its effects by significantly increasing the proportion of thick hair. In this study, we assessed the clinical outcome of adenosine treatment for 6 months in 38 Caucasian men. The change in the proportion of thick hair (60 pm) compared with baseline in the adenosine group was significantly higher than that in the placebo group (P c 0.0001). The change in vellus hair proportion (<40 pm) was significantly lower in the adenosine group than that in the placebo group (P = 0.0154). The change in hair density compared with a baseline of the adenosine group was also significantly higher compared with that of the placebo group (P = 0.0470). No adverse effects due to treatment were noted during this study by dermatological evaluation. Adenosine is effective In increasing the proportion of thick hair in Caucasian men with AGA as well as in Japanese men and women.
Keywords: Caucasian; adenosine; androgenetic alopecia; hair growth.
© 2015 Japanese Dermatological Association.
Topical adenosine increases thick hair ratio in Japanese men with androgenetic alopecia
Y Watanabe 1, T Nagashima 2, N Hanzawa 3, A Ishino 3, Y Nakazawa 3, M Ogo 3, T Iwabuchi 3 M Tajima 3
Affiliations+ expand
PMID: 25925959 DOI: 10.1111/ics.12235
Abstract
Objective: Hair thickness is more important than hair density in the appearance of baldness in male with androgenetic alopecia (AGA). Adenosine improves hair loss by stimulating hair growth and by thickening hair shafts in women. The objective of this study was to evaluate the hair growth efficacy and safety of topical adenosine in men with AGA.
Methods: A lotion containing either adenosine or niacinamide was administered to the scalps of 102 Japanese men twice daily for 6 months in a double-blind, randomized study. Efficacy was evaluated by dermatologists who assessed the quality of the hair and by calculating the percentages of vellus- like and thick hairs among the vertex hairs, as well as hair density.
Results : Adenosine was significantly (P < 0.05) superior to niacinamide in terms of global improvement of AGA, increase in the percentage of thick hairs (at least 60 pm) and self-assessment of hair thickness by the study participants. No causal adverse event due to the adenosine lotion was observed.
Conclusion: These data indicate that adenosine increases thick hair ratio in Japanese men with AGA, and this compound is useful for the improvement of AGA.
Adenosine stimulates the growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles
Kyung-A Hwang 1, YuI-Lye Hwang, Min-Ho Lee, Na-Ri Kim, Seok-Seon Roh, Young Lee, Chang Deok Kim, Jeung-Hoon Lee, Kyung-Chul Choi
Affiliations + expand
PMID: 22020741 DOI: 10.3892/ijmm.2011.817
Abstract
Hair regress : on and balding are distressing concerns for an increasing number of people due to changes in lifestyle and serious nutritional imbalances. Therapies for the treatment of hair loss are needed. Among potential therapeutics, adenosine has been suggested as a potent regulator of hair growth. In this study, we investigated the effects of adenosine on hair follicles and dermal papilla (DP) cells, and the mechanism underlying the action of adenosine. Hair follicles are organs, including DP cells that are responsible for the production of hair fibers by inducing and maintaining the hair growth phase (anagen). In a culture of DP cells in vitro adenosine stimulated the proliferation of DP cells by increasing thymidine uptake. Subsequently, adenosine activated and elongated the anagen phase by increasing the uptake of radiolabeled cysteine in an organ culture of mouse vibrissae hair follicles. We also confirmed that adenosine promoted the expression of several growth factors that are responsible for hair growth, including fibroblast growth factors (FGF)-7, FGF-2, insulin-like growth factor (IGF)-1, and vascular endothelial growth factor (VEGF) in a cDNA microarray with semi- quantitative RT-PCR. Transcriptional activation of 13-catenin in DP cells was increased by adenosine in a luciferase assay. p-catenin is a co-activator of Wnt/P-catenin signaling that induces morphogenesis and differentiation of hair follicles and also acts to transactivate downstream signaling pathways, including the ERK pathway. Using Western blotting, we found that adenosine stimulated phosphorylation of ERK. CREB and AC. These results suggest that adenosine stimulates the growth of hair follicles by triggering the expression of growth factors and 13-catenin, and by inducing their downstream target signaling pathways.
Esperienze Dermatologiche 2018 June;20(2 Suppl 1):27-30
DOI: 10.23736/S1128-9155.18.00459-4
Copyright (0 2018 EDIZIONI MINERVA MEDICA
language: English
Strengthening hair with Centella Asiatica: a report of clinical and subjective efficacy of local treatment with a 0.5% hair lotion
Stefano TOGNI 1, Giada MARAMALDI 1, Martino MENEGHIN 1, Roberto EGGENHOFFNER 2, Luca GIACOMELLI 2 la 7 Indian S.p.A., Milan, Italy, 2 Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy
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BACKGROUND : Hair follicles represent a regenerating organ, surrounded by a dense capillary network and sebaceous gland, with some capillaries penetrating to perfuse also the dermal papilla that promotes follicular growth. Centella Asiatica is an Ayurvedic herb of the Umbellifere family, containing high levels of the glycosylated triterpenes
Madecassoside and Asiaticoside, are known respectively to facilitate collagen III and boost collagen I synthesis at the perivascular tissue level. These properties improve follicle perfusion and metabolism, and thus extracts from Centella Asiatica may be helpful to strengthen and invigorate hair, with a strong potential for hair care applications. METHODS: Our study evaluated these targets by comparing the efficacy and tolerance/appreciation of a hair lotion containing Centella Asiatica extract (Centerox®), versus a placebo lotion, in 30 volunteers with telogen effluvium or mild to moderate alopecia, 15 per group. The volunteers used 2 ml of the assigned lotion each day over a period of 4-8 weeks. Efficacy was evaluated by means of the pull test and wash test, whereas tolerance was self-assessed with a questionnaire. Additionally, an in vitro study was performed to evaluate the ability of Centella Asiatica triterpenes to improve epidermal cohesion and dermal-epidermal junction on epidermal keratinocytes. RESULTS: The lotion containing Centella Asiatica allowed a 41% decrease in hair loss in the washing test, and a small increase in hair strength in the pull test (P<0.05). The product was well tolerated. A 33% increase in laminin-5 expression was also observed in the in-vitro study (P<0.05). CONCLUSIONS: Centerox® is effective and well-tolerated in the treatment of alopecia, resulting in improved hair strengthening and decreased hair loss. Moreover, triterpenes upregulate laminin-S, responsible for hair growth, due to their action in cell differentiation, migration, adhesion, and phenotypes expressions.
KEYWORDS: Centella Asiatica extract – Hair preparations – Alopecia
Coenzyme Q10 has anti-aging effects on human hair
M. Giesen, T. WeIg, E. S. Zur Wiesche, V. Scheunemann, S. Gruedl, Y. Oezkabakciogiu, E. Poppe, Dirk Petersohn
First published: 24 February 2009 https://doi.org/10.1111/j.1468-2494.2008.00451_5.x 1
Citations: 4 Abstracts of papers that were published in the IFSCC Magazine Volume 11, No 1, 2008
Abstract
IFSCC Magazine, 11 (2008) (1) 37-42
Ubiquinones are the most widespread and therefore best-investigated quinones. Due to their hydrophobic isoprenoid side chain, ubiquinones can be solubilized in organic solvents or lipids but are insoluble in water. Using a specific emulsifier system it has been possible to deliver positive effects to biological systems also from aqueous formulations. Ubiquinone-50, also referred to as coenzyme Q10, is well known in cosmetic science and especially in skincare because of its antioxidant activity. It is found in the membranes of peroxisomes, lysosomes, vesicles, the endoplasmic reticulum, and notably in the inner membrane of the mitochondrion, where it is an important part of the electron transport chain. Using Coenzyme Q10 in the proposed emulsifier system we could show that the molecule not only has relevance as an anti-aging bioactive in skincare but also has positive effects on the human hair follicle. The hair follicle is a complex mini-organ and the synthesis of hair keratin, the major component of hair fibers, is an essential prerequisite for the growth of strong and healthy hair. But like all biological systems the hair follicle, the biologically active part of the hair, also undergoes an aging process associated among other things with a decline in certain hair keratins. Due to this age-related shift in basic structural proteins of the hair shaft, mature hair often becomes fragile and difficult to manage. Therefore it is a challenge for cosmetic science to provide bioactive to fight age-related changes and maintain a youthful appearance of hair. Using cultivated hair follicle keratinocytes we identified coenzyme Q10 as a potent bioactive that stimulates the gene expression of different hair keratins, especially those which are reduced during aging processes in hair follicles. These results led us to investigate a shampoo and a tonic formulation enriched with coenzyme Q10 in a placebo-controlled panel study. In a left/right comparison, a group of healthy volunteers older than 40 years of age applied the formulations daily for 4 days. Throughout the test period, the gene expression of different hair keratins from plucked hair follicles was determined using quantitative polymerase chain reaction techniques. Subsequent statistical analysis revealed an increase in age-relevant hair keratins in human hair roots treated with coenzyme Q10, thus pointing out the striking benefits of coenzyme Q10 in hair care formulations. We conclude that coenzyme Q10 is an ideal ingredient for hair care formulations, providing anti-aging properties through the activation of specific keratins aligned with the needs of mature hair.
The Potential Application of Ecklonia cava Extract in Scalp Protection

Biospectrum Life Science Institute, U-TOWER 18th FL, 767, Since Ro, sup Gu, Yongin City, Gyunggi Do 16827. Korea

  • Author to whom correspondence should be addressed.
    Cosmetics 2020, 7(1), 9, https://dolorg/10.3390/cosmetics7010009 Received: 17 December 2019 / Revised: 16 January 2020 /
    Accepted: 17 January 2020 / Published: 20 January 2020
    Abstract
    The scalp is exposed to environmental hazards including airborne pollutants which exert adverse effects on skin health Therefore compounds for defending skin from pollutants have attracted interest in the cosmeceutical community We investigated whether Ecklonia cave exhibited prophylactic effects against urban pollutants by measuring cell viability and cell cycle distribution in human follicle dermal papilla cells (HFDPC) The effect of E. cave on pollutant-induced damage to skin barrier was determined by measuring filaggrin and MMP-1 expression in both keratinocytes and in a skin explant model In a clinical trial, the effect of E cave on scalp skin of patients with scalp scale was observed by evaluating hydration and redness after 4 weeks of daily treatment with a shampoo containing E cave extract E cave extract recovered the loss of cell viability and abnormal cell cycle distribution induced by urban pollutants in HFDPCs It also attenuated pollutant-induced damage to skin barrier by decreasing MMP-1 and increasing filaggrin expression in keratinocytes and the epidermis of skin explants Moreover E cave showed soothing effects on human scalp by increasing hydration and decreasing redness in a clinical trial Collectively. E cave extract may be a good candidate for therapeutic applications designed to repair or protect hair scalp Keywords Ecklonia cave, scalp urban dust. hydration. anti-inflammation
    Int J Mol Sc’ 2012; 13(5) 6407-6423. PMCID. PMC3382810 Published online 2012 May 23 dot 10.33.01iims13056407 PMID 2215.4373
    Effect of Dieckol, a Component of Ecklonia cava, on the Promotion of Hair Growth
    Jung-II Kang,1 Sang-Cheol Kim 1 Min-Kyoung Kim. Hye-Jin Boo 1 You-Jin Jeon.2.3 Young-Sang Koh 1 Eun-Sook Yoo 1 Sung-Myung Kang 3 and Hee-Kyoung Kang

    • Author information
    • Article notes
    • Copyright and License information
    • Disclaimer

This article has been cited by other articles in PMC.
Abstract,……………………..Go to
This study was conducted to evaluate the effect of Ecklonia cava. a marine alga native to Jeju Island in Korea. on the promotion of hair growth. When vibrissa follicles were cultured in the presence of E. cava enzymatic extract (which contains more than 35% of the director) for 21 days. E. cava enzymatic extract increased hair-fiber length. In addition, after topical application of the 0.5% E. cava enzymatic extract onto the back of C57BL ‘6 mice. anagen progression of the hair shaft was induced. The treatment with E. cava enzymatic extract resulted in the proliferation of immortalized vibrissa dermal papilla cells (DPC). Especially. director. among the isolated compounds from the E. cava enzymatic extract. showed activity that increased the proliferation of DPC. When NIH3T3 fibroblasts were treated with the E. cava enzymatic extract and the isolated compounds from the E. cava enzymatic extract. the E. cava enzymatic extract increased the proliferation of NIH3T3 fibroblasts. but the isolated compounds such as nickel. director. phloroglucinol and triphlorethol-A did not affect the proliferation of NIH3T3 fibroblasts. On the other hand. the E. cava enzymatic extract and dieckol significantly inhibited 5a-reductase activity. These results suggest that directors from E. cava can stimulate hair growth by the proliferation of DPC and/or the inhibition of 5a-reductase activity.
Keywords: Ecklonia cava. director. hair growth. dermal papilla cells. 5a- reductase activity. vibrissa follicle. C57BL/6 mice

In an ex vivo Philpott test, Redensyl° increases hair growth by +214% compared to untreated and shows almost two times higher results than Minoxidil, the benchmark reference.
Scalp pictures before and after clinical trial

  • Up to 9% increase in the number of anagen hair after 3 months
  • Up to 17% decrease in the number of telogen hair after 3 months
  • Up to 17% increase in hair density after 3 months
  • +10,200 average new hairs after 3 months
  • 85% of volunteers: reported a noticeable increase in hair growth

Disclaimer: Results may vary from person to person. Consistent daily usage and the right topical application method yield the best results.
DESCRIPTION: The Redensifying Hair Regrowth Serum is a powerful serum formulated to address hair loss issues by identifying hair for thicker and healthier growth. The serum features an award-winning patented ingredient Redensyl@, clinically proven to activate the proliferation of hair follicle stem cells: and to boost the metabolism of derma papilla fibroblasts. Saw Palmetto and EckIonia Cava Extracts block DHT, the root cause of hair loss while Biotin rejuvenates hair health for improved hair quality. Adenosine and Coenzyme Q10 work synergistically by boosting and facilitating ATP production to stimulate hair growth and provide antiaging protection on the scalp. Centella Asiatica Extract, known for its superior healing properties, also nourishes and moisturizes the scalp while strengthening the hair collides.
DIRECTIONS: Apply a generous amount directly onto dean, the dry scalp, especially in hair thinning areas. Gently massage the scalp with fingertips. For best results, use two times a day with at least eight hours between each application. Do not rinse any water and leave the serum on the scalp for at least four hours for maximum absorption. In case of accidental contact with eyes, rinse eyes thoroughly with cold water. We recommend using the serum daily twice a day for at least four to six months continuously to see results
IDENTIFYING HAIR REGROWTH SERUM
ACTIVE INGREDIENTS Rodonsyl
Saw Palmetto Extract
Ecklonia Cava Extract
Centella Asiatica Extract
Biotin
Adenosine
Ubiquinone (CoQ10)
Reactivate Hair Follicles
  Reduce Hair loss
Increase lifespan of Hair Follicles
  Redensify Hair
  Provide anti-aging protection on the stair
Improve scalp condition for healthy hair growth
Suitable for both men and women use 12 Formulated and Manufactured in
Singapore

All Hair Types 1 60 ml (2F1 OZ)

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